Not sure what you're asking.
5e is far and away the most coherent and playable, but it's still super heavy and has a lot of problems.
Matrix is better integrated into everyone else doing things.
Relatively easy to GM on the fly, as numbers tend to be from a relatively narrow range that's easier to improvise.
Chrome Flesh includes an augmentation called Liminal Body: Tank!, for which the exclamation point is part of the spelling, and that is awesome.
It's still MagicRun. There's no reason not to be a mage, and this edition, it's not a downward spiral of, "How long before your mage hits magic zero from bad rolls permanently costing you magic rating?"