Not if they succumb to the fate of product bloat. It happened in the last days of TSR, it happened to 3rd and 4th Edition with Wizards of the Coast; I have the feeling that history will repeat itself.
I don't see how they can possibly avoid it. Remember, WotC answers to Hasbro, and Hasbro has some pretty stringent standards for profitability. Give the guys at WotC due credit for managing to make a tabletop RPG meet those standards for so long, given that tabletop RPGs have never been a high-profit commodity.
4e was an attempt to radically shift their profit model from a "Buy a new book every month" arrangement to a monthly fee-for-service model, not unlike MMORPGs. However, that fell on its face spectacularly. D&D Insider never came close to the "virtual gaming environment" they promised, and even Gleemax collapsed.
That leaves them with the "Book a month until saturation, then reset" model...and the problems that prompted them to try getting away from that model in the first place. With every reset, they lose customers, and the time to saturation decreases. There's a reason 4e only lasted 3 1/2 years.
I made several predictions when 4e was announced. Unfortunately, most of them have been accurate. I say "unfortunately," because one of those predictions was that they'd have to go to a fifth edition fairly quickly, and that fifth edition would be the end of the line for the tabletop RPG. I still expect that to be the case, sadly.
