However, Fate Berseker gets beaten by a school kid with hardly any combat training and second-grade weapons. In two alternate dimensions, so should not be much of a challenge for Goku. EDIT:Ninjae'd.
Only if Goku's punch is an A-or-above ranked attack (literally, not power wise). Otherwise, Berserker won't so much as flinch.
God Hand is weird: you can hit it with an ancient Indian nuke (B rank, Vajra) and it does nothing. Caliburn, which is basically 'bright light', is fine. Though Archer cut through most of his lives in that scenario...
The black-haired lesbian bisexual magician gem-witch could punch trough god-hand as well. And last time I checked her lazors aren't anywhere near planet-busting like Goku has. She can't even nuke a city, at her best time she could destroy some giants. So if she going nova can remove one life from Berseker, Goku most certainly can take care of all of them.
EDIT: Archer used Gae-Bolg to finish off Berseker in yet another alternate reality, and that one was explicitly a rank B weapon.
Rin's gems, used in concert like that, are A-Ranked magecraft. Hence why she could do something.
It would be Lancer using Gae Bolg (not Archer), and he used rune magic to buff it to A-Rank.
The bottom line is that it's not a question of power (A++ is a beam cannon sword, flying lightning chariot, and self-buffing sword--yet B+ gets the 'kills you, then it stabs you' spear, and the nuke, and the area-of-effect temple that turns people into blood then magic) but whether it has a rank.
It's from a magazine, but this is the scenario you're referring to:
Q. Lancer, Caster, Assassin, and True Assassins; all with normal attack and Noble Phantasms of B or lower. If they fought against Berserker, wouldn't it be a one-sided fight? Or are there any of them that can match up against him?
A: Assassin and True Assassin by themselves wouldn't even be a fight. Lancer can use his runes and Noble Phantasm together to temporarily raise the rank to A, but it'd still be a very disadvantageous fight but "one with some chances". Caster has two front-line Saber-class defenders, so if she uses her high sorcery then she'd be able to deal damage, but that would be limited to 2 to 3 times. Also, in the game, Assassin was able to push Berserker back because of the terrain advantage and support from Caster (weighing down Berserker's body). ...Well, since the compatibility of Assassin and Berserker is horrible, the fact that Berserker was even pushed back is enough to say "whoah, Kojirou's amazing".
God Hand text, from an encyclopaedia/side book thing:
Immortality obtained from a blessing (curse) of the gods.
The body is transformed into strong armor, and all attacks of rank B and below are nullified.
Additionally, there is the extra effect where revival (Raise) is automatically cast upon death.
There is a stock of eleven revivals.
On a side note, Goku couldn't actually work his way through all 12 lives, even if the punch
is A-rank, unless he somehow manages to do that in one attack. Because otherwise Herc would be immune afterwards. Strange, really.